Repurposed Drug Protocols
REPURPOSED DRUGS & INTEGRATIVE ONCOLOGY

Repurposed Drug & Supplement Protocols by Dr. William Makis

Pioneering targeted integrative care using evidence-informed repurposed medications (Ivermectin, Fenbendazole, Mebendazole, Hydroxychloroquine) paired with high-potency supplement stacks to target cancer bioenergetics and cellular resilience.

Fenbendazole & Joe Tippens Protocol
ANTIPARASITIC CANCER PROTOCOLS

The Fenbendazole & Joe Tippens Protocols

Disrupting tumor microtubule polymerization and cellular glucose transport through structured antiparasitic cycling, fat-solubility enhancement, and synergistic antioxidant stacks.

Spike Protein Detox Protocol
DETOXIFICATION & CELLULAR RECOVERY

Spike Protein & Vaccine Detoxification

Medically supervised detox programs combining Nattokinase, Bromelain, NAC, Ivermectin, and targeted organ-protective nutraceuticals to dissolve protein aggregates and support microvascular recovery.

Targeted Supplement Stacks
PRACTITIONER-GRADE NUTRACEUTICALS

Targeted Supplement Stacks for Protocol Support

High-potency Curcumin, Quercetin, Zinc, Vitamin D3/K2, Berberine, and TUDCA specifically formulated to optimize protocol tolerance, liver health, and anti-inflammatory pathways.

Repurposed Medications & Targeted Supplement Care

Medically Supervised Antiparasitics, Metabolic Modulators & High-Potency Nutraceuticals

DR. WILLIAM MAKIS' CLINICAL APPROACH

Targeting cancer cell metabolism, microtubule dynamics, and stem cell pathways using well-studied repurposed compounds.

Repurposed medications such as Ivermectin, Fenbendazole, Mebendazole, and Hydroxychloroquine have demonstrated significant anti-tumor and immunomodulatory mechanisms in preclinical and clinical literature.

By combining structured medication cycling with targeted organ support (TUDCA, NAC, Milk Thistle) and synergistic nutraceuticals (Curcumin, Quercetin, Berberine), Dr. William Makis constructs personalized treatment roadmaps designed for optimal biological efficacy.

Integrative Framework Dr. William Makis, MD

Repurposed Drug Synergy Matrix

Combining antiparasitic compounds (Ivermectin, Fenbendazole, Mebendazole) with metabolic regulators and cellular detoxification agents for multi-pathway cancer targeting.

Tubulin & Microtubule Inhibition Fenbendazole & Mebendazole block tumor mitosis & glucose uptake.
Cancer Stem Cell Signaling Blockade Ivermectin inhibits Wnt/β-catenin and Akt renewal pathways.
Organ Protection & Fibrinolysis TUDCA, Milk Thistle, Nattokinase & Bromelain safeguard liver & vascular health.
Evidence-Informed Protocol Roadmaps Explore Protocols →
01

ANTIPARASITIC & ANTI-MITOTIC

Benzimidazoles & Avermectins

Fenbendazole, Mebendazole, and Ivermectin target tumor tubulin assembly, disrupt glucose utilization (GLUT-1), and inhibit Wnt/β-catenin signaling in resistant cancer cell populations.

02

METABOLIC MODULATION

AMPK & Glycolysis Regulation

Utilizing Hydroxychloroquine, Berberine, and Metformin to disrupt tumor autophagic rescue mechanisms, suppress lactate production, and starve metabolic cancer pathways.

03

DETOX & ORGAN PROTECTION

Spike Detox & Hepatic Shield

Targeted proteolytic enzymes (Nattokinase, Bromelain) and hepatoprotective compounds (TUDCA, NAC, Glutathione) prevent Herxheimer reactions and protect liver function during active protocol cycling.

CLINICAL INSIGHTS & PRESENTATIONS

Watch Dr. William Makis, MD

Watch recent video shorts and clinical discussions with Dr. William Makis on repurposed medications, targeted cancer protocols, and spike protein detoxification.

PRACTITIONER-GRADE FORMULATIONS

Targeted Protocol Supplements

High-purity, bioavailable nutraceuticals specifically selected by Dr. William Makis to enhance protocol synergy and organ protection.

Fenbendazole

Fenbendazole

$650.00

Fenbendazole is a broad-spectrum benzimidazole anthelmintic currently being extensively researched worldwide for its potential complementary applications in various health protocols. It works by binding to tubulin, interfering with cellular division mechanisms.

Ivermectin Support (3mg & 12mg)

Ivermectin Support (3mg & 12mg)

$250.00

Ivermectin is an FDA-approved antiparasitic drug that has gained significant attention for its off-label use in various supportive and preventative health protocols. It is being studied for its unique ionophore properties.

Ivermectin 3mg

Ivermectin 3mg

$250.00

Ivermectin is an FDA-approved antiparasitic drug that has gained significant attention for its off-label use in various supportive and preventative health protocols. It is being studied for its unique ionophore properties.

Ivermectin 6mg

Ivermectin 6mg

$250.00

Ivermectin is an FDA-approved antiparasitic drug that has gained significant attention for its off-label use in various supportive and preventative health protocols. It is being studied for its unique ionophore properties.

Dr. William Makis

PHYSICIAN & RESEARCH LEAD

Meet Dr. William Makis, MD

MD, FRCPC | Repurposed Medications & Integrative Oncology

Dr. William Makis, MD, FRCPC is a Canadian physician and medical researcher specializing in nuclear medicine, radiology, and targeted cancer therapeutics. With over 100 peer-reviewed medical publications, Dr. Makis is an internationally recognized pioneer in repurposed medication protocols for oncology and spike protein detoxification.

Through comprehensive clinical consultations, Dr. Makis evaluates individual medical histories, pathology reports, and biomarker data to construct evidence-informed repurposed drug and supplement roadmaps.

Read Dr. Makis' Full Bio & Research

RESEARCH & MEDICAL INSIGHTS

Latest Blog Posts & Articles

View All Blog Posts →
Repurposed Medications in Integrative Oncology
Video Included
Aug 11, 2026
BLOG

Repurposed Medications in Integrative Oncology

Dr. William Makis explains repurposed drug protocols.

NEW ARTICLE: Ivermectin and Fenbendazole Testimonial – Stage 4 GastroEso...
Jul 22, 2026
BLOG

NEW ARTICLE: Ivermectin and Fenbendazole Testimonial – Stage 4 GastroEso...

Not every Ivermectin Cancer success story is a happy success story. The body can improve but the mind may not always follow.Pat...

COMMON QUESTIONS

Frequently Asked Questions

Clear answers regarding oncologist collaboration, telemedicine availability, record requirements, timeline, and protocol personalization.

START YOUR PERSONALIZED PROTOCOL

Ready to Explore Repurposed Drug Protocols with Dr. William Makis?

Schedule an in-person appointment in San Francisco, CA or request a secure telemedicine record review to receive your individualized treatment roadmap.